Tillerson is a veteran chief executive who has had extensive overseas business dealings but his relationships with foreign leaders could complicate his confirmation prospects.
Tillerson, 64, who was confirmed by the Senate in a 56-43 vote, was administered the oath of office by Vice President Mike Pence.
Propelled to the position of the Secretary of State to "undo" years of American foreign policy "blunders and disasters", ExxonMobil CEO Rex Tillerson now faces the biggest challenge of his life to translate his business acumen to international diplomacy.
Like Mr Trump, says Kanika Datta, politics tempts many businessmen.